Boruto : Naruto Next Generation : Siapa Isshiki Otsutsuki? Apa Hubungannya dengan Kaguya?
Jadi, pada dasarnya Isshiki dan Kaguya adalah pasangan yang ditugaskan untuk membawa kembali buah chakra dari Bumi.
Kaguya adalah antagonis utama dari Serial Naruto Shippuden.
Kaguya sangat kuat dan seperti Dewa, tapi Isshiki adalah salah satu yang lebih kuat dari orang tersebut.
Otsusuki datang berpasangan karena yang satu bertindak sebagai tuan rumah bagi sepuluh ekor dan yang lainnya menjaga dan membudidayakan buah.
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